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Current Diagnostics Can’t
Predict Therapy Response for
most Heterogeneous Tumours

Why is it so hard to predict cancer therapy response?

Because most tumors are made up of lots of different cell types, not just “cancer cells”. This is called “tumor heterogeneity”.

For example, pancreatic cancer only contains 5-15% actual cancer cells; the rest being immune cells, fibroblasts, blood vessels, and other cell types. 

This also affects other indications, such as bladder cancer, triple-negative breast cancer, non-small-cell lung cancer, and many more. 

Current Diagnostics…

… blend all of these different cell types together into a kind of “smoothie”. This loses a lot of sensitivity and resolution.

Our Technology…

… can look at the individual cells in the tumor. More like a fruit salad!

Actually, 2NA FISH is even better:

We can see the spatial arrangement of these cells in the tumor – the “tumor microenvironment” and how the cells interact with each other!

Our Value Proposition

Mid-plex spatial RNA

Integrates genomics + tissue context

Single-cell Resolution

Traces signal back to cell types + higher sensitivity

7+ Targets in 1 Biopsy

Gets the most out of limited material

Single-cell analysis
in situ can reveal
rare high-expressing cells
that bulk averages miss

Our software decodes the
Molecular Barcode and provides a simple, quantitative analysis
within hours

Cell Her2 Count
1 50
2 70
3 30
4 300
5 60
6 290
...
113 40
AVG 134

Single-cell resolution lets you
find rare HER2-
Overexpressing Cells

Cell Her2 Count
1 50
2 70
3 30
4 300
5 60
6 290
...
113 40
AVG 134

With 2NA FISH’s single-cell resolution, individual cells with extremely high expression of an RNA biomarker, e.g. HER2, can be identified. 

Features

  • Multiplexed, in situ RNA detection
  • No microfluidics or special instruments necessary - runs on standard epifluorescence microscopes
  • Single-cell resolution - Count the number of transcripts per cell

Use our
Snappy Web App for
Fast Analysis

From image upload to cell-level readouts in minutes - built for
translational research. (RUO)

Features

Our browser-based app streamlines spatial RNA analysis on the microscopes you already use. Upload images, review QC, and explore single-cell patterns with clean, lab-friendly workflows – no special hardware or complex installs. 

  • Frictionless upload: Drag-and-drop TIFFs for each experimental group
  • Cell-level exploration: Inspect transcript patterns by region or cell type without leaving the browser.
  • Clear summaries: Instant plots and downloadable analyses for figures, lab meetings, and grant updates.

Wanna Test Out Our
Cutting-Edge Technology?
Are You...

A Researcher...

...who wants to resolve gene activity spatially without remodeling your whole lab?

Click Here to Get Bright Insights Into Your Cells – Book an Intro Call!

A Therapy Developer...

...frustrated by the high cost of clinical studies?

Book a Consultation With Our Specialists!

A Medical Doctor...

...wanting to collaborate on developing and testing a cutting-edge diagnostics test that saves patient lives?

Book an Intro Call to Discuss Collaborations!

The Right Team to Transform
Cancer Diagnostics

Dr. Christina Port

CEO

Entrepreneur, inventor of 2NA FISH, expert in RNA FISH & DNA nanotechnology

  • 12+ years in molecular biology/biotech published in top-tier journals
  • 1 patent application
  • Raised €1.6M+ in grants. & investment
  • 60k€ revenue/year with own e-commerce brand “Zen Garden”
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Dr. Christina Port

Dr. Antonia Malinova

Lead Scientist

Expert in Cancer Biology, Organoids & Imaging technologies

 

  • First-author Nature paper
  • Marie-Curie Fellowship
  • Expert in organoid models, RNA FISH and tumor biology
  • Project management at Abbott Diabetes Care, UK
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Dr. Antonia Malinova

Gamze Naz Öztan

Staff Scientist

Berkay Arslan

Assistant Scientist

Bernhard Saumweber

Software Architect & Lead

Nicolai Ommer

Software Architect

Sara Kosanovic

Computer Vision, Master student

Julia Weinbrenner

Founder's Associate

FAQ

  • Do I need special hardware? No—standard epifluorescence microscopes used in pathology labs are sufficient for our RUO workflow.

  • How many targets can I run? We support mid-plex panels today; details are shared under NDA for pilot partners.

  • What about analysis? A browser-based app handles upload, QC, exploration, and reporting. 

  • Clinical use? Our assays are For Research Use Only and not for diagnostic procedures.

2NA FISH Saves Lives Through
the Development of Novel
Diagnostics for all Types of
Heterogeneous Cancers

Disclaimer: 2NA FISH Technology at the moment is intended for Research Use Only (RUO). 

Join Us in Revolutionizing
Cancer Therapy!

Book an Intro Call now!

Contact us:

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